SPR technology in Biacore systems is used to analyze interactions between molecules ranging from ions to viruses.
The technology provides information about kinetic data, affinity, specificity and concentration.
BIACORE T100
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use Surface Plasmon Resonance technique
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analyzes any type of biomolecular interaction
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works at different temperatures (4-45°C)
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marking not necessary
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use small volumes and small quantities of biomolecules
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It provides kinetic and thermodynamic data in real time
APPLICATIONS:
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kinetic and thermodynamic analysis of biomolecular interactions
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analyzes of small target molecular interactions with specific targets
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analysis of Small Molecule interactions with specific targets
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analysis of interactions with biological membranes
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screening of compounds and / or drugs
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evaluation and comparison of quality and structure-function in production batches
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evaluation of the antibody response in patient sera and antibody isotyping
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follow-up and support to clinical trials with certified final report
Work on behalf of third parties since 2009
Quality certification UNI EN ISO 9001:2015 since 2016
Biacore™ T200 Upgrade
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sensitivity increase (concentration > 1 pM)
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analyze interactions involving very low molecular weight molecules
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greater versatility/flexibility
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excellent accuracy over a wide kinetic range (LMW molecules: kada 103a 5×107M-1s-1; Proteins: kada 103a 3×109M-1s-1; kdda 10-5a 1 s-1)
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immunogenicity Testing Tools
BiacoreT200 GxPPackage
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validated software with increased data security
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traceability of methods and data obtained